I have many buyers that are aware of the NIOSH list and do a great job of keeping the pharmacy safe from packaging dangerous drugs. I find myself sharing this link often to keep myself and my buyers aware of current potentially hazardous drugs. 

So, What is the NIOSH list? The National Institute for Occupational Safety and Health (NIOSH) is responsible for conducting research and making recommendations for the prevention of work-related injury and illness.

NIOSH identifies potentially hazardous drugs. Potentially hazardous drugs are those for which the manufacturer has provided special handling information intended to protect workers, or for which available toxicity information suggests that a drug may exhibit one of the types of toxicity in the NIOSH definition of a hazardous drug.

Group 1: Antineoplastic drugs (AHFS Classification 10:00) [ASHP/AHFS DI 2016]. Note that many of these drugs may also pose a reproductive risk for susceptible populations (Table 1).

Group 2: Non-antineoplastic drugs that meet one or more of the NIOSH criteria for a hazardous drug. Note that some of these drugs may also pose a reproductive risk for susceptible populations (Table 2).

Group 3: Drugs that primarily pose a reproductive risk to men and women who are actively trying to conceive and women who are pregnant or breast feeding, because some of these drugs may be present in breast milk (Table 3).

See the link for the most up to date information and current drugs on the NIOSH list. 


Here is a list of the unit dose generic drugs that AvKARE offers: 

Table 1. Group 1: Antineoplastic drugs, including those with the manufacturer’s safe-handling guidance (MSHG)

Table 1:

  • Anastrozole 
  • Imatinib
  • Letrozole
  • Temozolomide

Table 2. Group 2: Non-antineoplastic drugs that meet one or more of the NIOSH criteria for a hazardous drug, including those with the manufacturer’s safe-handling guidance (MSHG)

Table 2: 

  • Divalproex
  • Raloxifene
  • Risperidone
  • Sirolimus
  • Valganciclovir

Table 3. Group 3: Non-antineoplastic drugs that primarily have adverse reproductive effects

Table 3:

  • Dutasteride
  • Finasteride
  • Fluconazole
  • Paroxetine
  • Zonisamide